TD-5471 HYDROCHLORIDE - AN OVERVIEW

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Jamieson described the development of MF while in the context of the JAK/STAT network. “This pathway is upregulated in the vast majority of people Using these myeloproliferative neoplasms. In some, It can be based on a mutation in JAK2 that stops the gene from remaining turned off; in Other individuals, a mutation in CALR can also activate JAK/ST